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Genozip

A modern compressor for genomic files (FASTQ, SAM/BAM/CRAM, VCF, FASTA, GFF/GTF/GVF, 23andMe...), up to 5x better than gzip and faster too

From divonlan·Updated June 23, 2026·View on GitHub·

Genozip is a lossless compressor for FASTQ, BAM/CRAM, VCF and many other genomic files - see https://genozip.com The project is written primarily in C, distributed under the Other license, first published in 2019. Key topics include: 23andme, bam, bgzip, bwa, compression.

Latest release: genozip-15.0.86— 15.0.86
June 22, 2026View Changelog →
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Current Release Conda Downloads

<h1>Genozip</h1><br> <br> <b>Genozip</b> is a lossless compressor for FASTQ, BAM/CRAM, VCF and <a href="https://www.genozip.com/compression">many other genomic files</a> - see https://genozip.com<br> <br> Genozip is also available on <b>Conda</b> and binary downloads, see <a href="https://genozip.com/installing">installation options</a>.<br> <br> Building from source: make -j (required for building: gcc 8.5 or above ; nasm).<br> <br> <h2>New: <a href="https://genozip.com">Genozip 15</a> - with Deep™ - losslessly co-compressing BAM and FASTQ files:</h2>

v15 deep benchmark

<b>Genozip</b> is a commercial product, but it is free for students. See <a href="https://genozip.com/academic">eligibility</a> and <a href="https://genozip.com/get-genozip">other licensing options</a> or contact <a href="mailto://sales@genozip.com">sales@genozip.com</a> <br>
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<b>IMPORTANT</b>: Genozip is a commercial product, <b>NOT AN OPEN SOURCE</b> product - we provide our source code to assure users that they will always have access to the code needed to decompress their files. <b>HOWEVER</b>, forking, reverse engineering, code modifications, derivative works or inclusion of the code or parts thereof into other software packages is strictly forbidden by the <a href="https://genozip.com/license">license</a>.<br>
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Attributions for 3rd party source components: <a href="https://genozip.com/attributions">attributions</a>.<br>
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<b>THIS SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, TITLE AND NON-INFRINGEMENT. IN NO EVENT SHALL THE AUTHORS, COPYRIGHT HOLDERS OR DISTRIBUTORS OF THIS SOFTWARE BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.</b><br>

Contributors

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divonlan

divonlan

3.2k commits

awensaunders

awensaunders

1 commits

gavrie

gavrie

1 commits

yassineS

yassineS

1 commits

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This article is auto-generated from divonlan/genozip via the GitHub API.Last fetched: 6/23/2026